Powerful enzyme formula that conveniently and effectively inhibits bacteria, fungus and yeast microbes that cause ear infections. Zymox® Otic is a No Clean, Once-A-Day Treatment. Works against antibiotic-resistant microbes, including Staphylococcus Aureus, E. Coli, Streptococcus Pyogenes, Pseudomonas Aeruginosa, Streptococcus Intermedius, Corynebacterium Diphtheriae, Proteus Miabilis, Malassezia Pacydermatis and Candida Albicans. Zymox® Otic (Hydrocortisone Free) is also safe for extended, preventive use for chronic Otitis Externa. Safe for all ages and species of pets.